Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor Employed in the therapy of numerous myeloma. Its synthesis or study is very important for guaranteeing the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor while in the synthesis of abiraterone acetate, a drug used in the treatment of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound inside the synthesis of imatinib, a drug that targets certain varieties of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They are intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the creation process and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is utilised to take care of breast cancer, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the cure of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain 4-[2-(2-Amino-4 Acid (CAS NO. 949023-sixteen-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in dealing with cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the treatment of colorectal most cancers and little cell lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, which have various programs, which includes antiviral Houses.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar stages.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of various gluconic acid derivatives, that are used in food items, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a GeMcitabineInterMediate9 medication used to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).